With over 50 million people struggling to control acne in the US, Arazlo lotion is a welcome addition to the tazarotene family of topical prescriptions. It combines tazarotene (a retinoid) with a unique oil-in-water emulsion technology to provide effective results while hydrating the skin.
What is Arazlo lotion?
Arazlo lotion is a prescription-strength medication that targets the root causes of acne. It is formulated to penetrate deep into the skin, unclogging pores and reducing inflammation. By regulating skin cell turnover, which is a main contributor to acne formation, Arazlo lotion helps prevent the formation of new acne lesions and promotes a clearer complexion.
Arazlo lotion’s unique formulation evening distributes ingredients, leaving behind a lightweight and non-greasy finish. This makes it convenient for daily use and suitable for all skin types. Whether you have oily, dry, or combination skin, Arazlo lotion can be incorporated into your skincare routine to manage acne effectively.
Key Ingredient in Arazlo lotion
Arazlo’s key active ingredient, tazarotene, is a retinoid (vitamin A derivative) that slows cellular overgrowth thus decreasing the potential for the pore to clog in the first place. In the diagram below labeled “Acne Formation”, cell overgrowth is the first step to a blemish forming. Tazarotene normalizes this process stopping acne in its tracks. It also has anti-inflammatory properties helping to reduce redness and swelling in the last stage of acne formation. Tazratoene helps treat and prevent noninflammatory (blackheads and whiteheads) and inflammatory acne (papules, pustules, cysts, nodules) acne.
Bonus: A bonus effect of tazarotene is that it promotes smoother skin texture and a more even skin tone!
The formation of acne is complex, but research suggests four main contributors to acne: cell overgrowth, oil (sebum) production, Cutibacterium acne (C. acne is a type of bacteria), and inflammation. Let’s review this process:
Step 1: The hair follicle cells shed too quickly and clog up the pores. Oil (sebum) gets trapped in these cells and further clogs the pores.
Step 2: Unfortunately, C. acne bacteria loves sebum, grows very well in that environment, and starts to multiply.
Step 3: The body’s immune system attacks the bacteria and inflammation forms leading to inflamed acne (papules, pustules, cysts, and/or nodules).
What makes Arazlo lotion unique?
Arazlo lotion was designed with a few unique features allowing for better results and less dryness/irritation which has been a challenge for patients using retinoids (retinol, tretinoin, tazarotene). According to Arazlo, its “polymeric emulsion technology distributes tazarotene evenly to help reduce irritation and facilitates rapid absorption…”
In addition to this technology, Arazlo lotion contains hydrating ingredients (see below) that work together to lock in moisture, prevent water loss, and improve barrier function minimizing irritation and dryness commonly associated with retinoid treatments:
- Diethyl Sebacate is an emollient. Emollients protect the outer layers of the skin and keep your skin soft and smooth.
- Mineral oil is an occlusive moisturizer that works as a barrier to help prevent moisture evaporation. It doesn’t clog the pores and helps keep your skin hydrated preventing dryness and irritation.
- Sorbitol is a humectant that attracts water to the top layer of the skin and locks it there to keep it moisturized for extended periods.
Arazlo lotion is lightweight and non-greasy despite containing many moisturizing ingredients. By combining tazarotene with these ingredients in its patented distribution technology, Arazlo lotion offers a new option to those fighting to control their acne!
What conditions does Arazlo lotion treat?
Arazlo lotion is indicated for the topical treatment of acne vulgaris in patients 9 years of age and older. Acne is a common skin condition affecting hundreds of millions worldwide. It can be emotionally and physically painful significantly impacting one’s self-esteem.
Other skin conditions tazarotene is used to treat:
- Psoriasis- FDA approved to treat plaque psoriasis
- Facial wrinkles
- Sun-induced hyperpigmentation
- Acne induced post-inflammatory hyperpigmentation (brown spots)
- Melasma
Warnings and Precautions when using Arazlo?
While Arazlo lotion is generally well-tolerated, it's essential to be aware of potential precautions and side effects. Always contact your medical provider with any questions or concerns.
- Some individuals may experience mild skin irritation, dryness, or redness during the initial use. These effects usually subside as your skin adjusts to the treatment.
- Do not use Arazlo lotion if you’re allergic to vitamin A derivatives (retinoids).
- Arazlo lotion should not be used by women who are pregnant or want to become pregnant.
- Minimize exposure to ultraviolet light, including sunlight, sunlamps and tanning beds. Consistent use of SPF 30 or higher is recommended. If you have to be in sunlight, wear a wide-brimmed hat and/or other protective clothing in addition to SPF.
- Avoid waxing (hair removal) to areas treated with Arazlo lotion.
- Arazlo may make your skin more sensitive to extreme weather (i.e. cold wind).
- Do not apply Arazlo lotion around your eyes, the area around the base of your nose, and the corners of your mouth.
- Apply at night. Sunlight (UV exposure) breaks down tazarotene by chemically altering the composition of retinoids, making them less effective.
Is Arazlo (tazarotene) safe to use long-term?
Topical retinoids (tazarotene) are widely considered safe for long-term use. Research in young adults showed that no systemic side effects have been observed in the past 30 years with long-term retinoid use.4
How to apply Arazlo lotion?
To get the best results from Arazlo lotion, follow these simple steps:
- Wash your face gently with a mild cleanser and pat it dry. (Hint: Make sure you allow your skin to dry completely. Applying retinol to wet or damp skin can increase absorption and cause irritation.)
- Apply a thin layer of Arazlo lotion to the affected areas once a night as your doctor advises. Remember…a little goes a long way.
- Apply a gentle moisturizer as needed.
- Wash your hands after applying.
- Apply SPF 30 or higher daily as retinoids can increase sun sensitivity.
*These recommendations are meant to complement, not replace, the advice given by your healthcare provider*
How much does Arazlo lotion cost?
Arazlo lotion is not available over-the-counter (OTC). Arazlo is a topical prescription medication, and you will need a prescription from a medical provider to buy it. If you’re struggling with acne, please contact our Dermatology team online. We can help at Piction Health!
According to GoodRX…Arazlo lotion is expensive! However…there are some great options to significantly lower the cost offered through the RX Access Program. Ortho Dermatologics, the manufacturer of Arazlo, offers significant discount pricing from $25 to $75. It’s worth checking out!
We strongly recommend reviewing the terms and conditions on Ortho Dermatologics’ website before using the coupons. Familiarize yourself with the guidelines and regulations associated with using Arazlo coupons. Piction Health is not responsible and cannot influence the price of the medication as it is independent of these entities.
Piction Health: Online Dermatology Care
Arazlo is a powerful acne-fighting lotion delivered in a hydrating formula. It can significantly improve your skin health and address your acne concerns. Contact our dermatologists to experience the benefits of Arazlo lotion and achieve clearer more radiant skin!
Piction Health offers online dermatology care, connecting you with experienced dermatologists who can guide you to healthier skin.
FAQ’s
Q: Can Arazlo lotion be used daily?
A: Yes, Arazlo lotion is designed for daily use.
Q: Is Arazlo lotion suitable for all skin types?
A: Arazlo lotion is formulated to be suitable for most skin types, including sensitive skin.
Q: Can Arazlo lotion be used during pregnancy?
A: No retinoids (including Arazlo lotion) should be used during pregnancy as they could potentially disrupt fetal development. Always discuss products you may use during pregnancy with your OB/GYN or midwife.
Q: Is Arazlo lotion expensive?
A: Yes, Arazlo lotion is expensive but Ortho Dermatologics, the manufacturer of Arazlo, offers RX Access Program which provides a significant discounted price between $25 to $75.
Q: Is Arazlo (tazarotene) safe to use long-term?
A: Topical retinoids (tazarotene) are widely considered safe for long-term use.
Q: Is tazarotene (Arazlo) better than tretinoin?
A: Tretinoin and tazarotene are both retinoids and are thought to be equally effective as a once daily treatment option for acne. In general both are excellent choices, but here are a few differences:
- Tazarotene 0.1% is considered the strongest retinol available…stronger than tretinoin 0.1%.
- Tazarotene is FDA approved to treat plaque psoriasis.
- Patients may respond to tazarotene when tretinoin treatment “failure” occurs.
- Tazarotene has been shown to be slightly more irritating to the skin compared to tretinoin when first starting out use.
- Tazarotene is offered in limited strengths compared to tretinoin.
- Arazlo is offered in a unique hydrating delivery system that evenly distributes active ingredients in a moisturizing formula.
PICTION HEALTH VIRTUAL DERMATOLOGY
For convenient access to professional dermatology care, visit Piction Health's online dermatology platform. Our board-certified dermatologists are ready to provide personalized guidance for your dermatology concerns. Schedule an online dermatology consultation today to take the first step towards healthier, happier skin.
References
- https://www.goodrx.com/arazlo
- https://www.arazlo.com/about-acne/
- American Academy of Dermatology Association. Skin Conditions by the Numbers. Date Accessed August 23, 2022.
- Mukherjee, S., et al. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical Interventions in Aging. (December 2006).
Disclaimer
The information provided on this medical blog is for educational and informational purposes only and is not intended as medical advice. While we strive for accuracy, medical knowledge constantly evolves, and individual health situations vary. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay seeking it because of something you have read on this blog. The authors and publishers of this blog are not responsible for any adverse effects or consequences resulting from using any suggestions, products, or procedures discussed in this blog.
